Structural and functional changes and their cellular and molecular mechanisms during cardiac senescence / 中华老年医学杂志

Cardiac senescence can change the structure and function of the heart and increase the risk of cardiovascular disease.Cardiac senescence is not only closely related to telomere damage, oxidative stress, mitochondrial dysfunction and autophagy, but also is regulated by non-coding RNA.Therefore, this article will give an overview of cardiac senescence and relative pathogenetic mechanisms, in order to provide new ideas for preventing and treating cardiac senescence and for achieving healthy and longevity.